| CLIOQUINOL-BP | |
| CAS NO : 130-26-7 | FORMULA : C9H5CllNO |
| GRADE : BP | FORMULA WT : 305.5 |
| TEST | SPECIFICATION |
| Description | Almost white, light yellow, brownish yellow or yellowish-grey powder |
| Solubility | Practically insoluble in water Sparingly Soluble in methylene Chloride, very slightly soluble or slightly soluble in ethanol (96%) |
| Identification | Complies |
| Assay (ODB) | 98.0-102.0% |
| Acidity or alkalinity | Complies |
| Related substance | Impurity A : 2.0% Impurity B : 1.0% Impurity C : 1.0% Unspecified impurities: 0.10% Total nominal content of impurities A,B,C & unspecified impurities: 3.0% Disregard limit: The area of the principal peak in the chromatogram obtained with reference solution (c) : 0.05% |
| Halides | Max 0.014% |
| Loss on drying | Max 0.5% |
| Sulphated ash | Max 0.1% |
| CLIOQUINOL-IP | |
| CAS NO : 130-26-7 | FORMULA : C9H5CllNO |
| GRADE : IP | FORMULA WT : 305.5 |
| TEST | SPECIFICATION |
| Description | A yellowish white to brownish yellow powder;odour, faint and characteristic. |
| Solubility | Freely soluble in dimethyl formamide and in pyridine; practically insoluble in ethanol (95 per cent) and in water. |
| Identification | Complies |
| Assay (ODB) | 97.0-103.0% |
| Acidity or alkalinity | Complies |
| Free iodine | Complies |
| Halide ions | Complies |
| Related substance | 1) The total content of the named impurities does not exceed 3.0% w/w, 2)The content of any other impurity does not exceed 0.2 % w/w 3)The sum of the contents is not more than 4.0 % w/w. |
| Sulphated ash | min.0.2% |
| Loss on drying | min.0.5% |
| CLIOQUINOL-USP | |
| CAS NO : 130-26-7 | FORMULA : C9H5CllNO |
| GRADE : USP | FORMULA WT : 305.5 |
| TEST | SPECIFICATION |
| Description | Volminous, spongy,Yellowish-white to brownish-yellow powder having a slight, characteristic odour. Darkness on exposure to light. Melts at about 1800c with decomposition |
| Solubility | Soluble in hot ethyl acetate & in hot glacial acetic acid, Practically insoluble in water & in alcohol. |
| Identification | Complies |
| Assay (ODB) | 93.0-100.5% |
| Residue on ignition | Max 0.5% |
| Loss on drying (1500c,6 hrs): | max 0.5% |
| Free iodine & iodide | max 0.05% of Iodide |